The goal of this course is to explore how chemical methods and concepts have impacted our ability to understand and manipulate protein structure and function. We will navigate this subject through a combination of lectures and structured discussions on research articles from the literature. The course is divided into three segments: (1) In the first part, we will review the rudiments of protein structure and function, then delve into various aspects of enzyme chemistry and polypeptide biosynthesis. (2) In the second part of the course, we will cover synthetic methods to produce and chemically modify peptides and proteins. (3) In the final part, we will discuss chemical approaches to control protein function and monitor protein activity, focusing on methods that use small molecules and mass spectrometry proteomics.
Prerequisites: CHEM UN2443 , or the equivalent. This is an introductory course to the emerging field macromolecular materials chemistry. The general topics will be based on the chemistry, self-assembly, and performance of block copolymers and conjugated polymers. Particular emphasis will be devoted to the demands required to drive materials from scientific curiosity to commercialization. At the fundamental level, the course will cover topics on polymerization techniques, electronic structure of organic semiconductors, characterization strategies, nanostructures and self-assembly.
Prerequisites: CHEM UN2443 , or the equivalent.
This class will describe the electronic and physical structure of inorganic materials with an emphasis on colloidal quantum dots and surface science.
Prerequisites: CHEM GU4221 Atomic and molecular quantum mechanics: fundamentals of electronic structure, many-body wave functions and operators, Hartree-Fock and density functional theory, the Dirac equation.