BIOMEDICAL ENGINEERING I
Various concepts within the field of biomedical engineering, foundational knowledge of engineering methodology applied to biological and/or medical problems through modules in biomechanics, biomaterials, and cell & tissue engineering.
- MW 10:10 a.m.-11:25 a.m.
- 3 points
BIOMEDICAL ENGINEERING LAB I
Fundamental considerations of wave mechanics; design philosophies; reliability and risk concepts; basics of fluid mechanics; design of structures subjected to blast; elements of seismic design; elements of fire design; flood considerations; advanced analysis in support of structural design.
- W 1:10 p.m.-3:55 p.m.
- R 1:10 p.m.-3:55 p.m.
- 3 points
BIOMEDICAL ENGINEERING DESIGN
A two-semester design sequence to be taken in the senior year. Elements of the design process, with specific applications to biomedical engineering: concept formulation, systems synthesis, design analysis, optimization, biocompatibility, impact on patient health and comfort, health care costs, regulatory issues, and medical ethics. Selection and execution of a project involving the design of an actual engineering device or system. Introduction to entrepreneurship, biomedical start-ups, and venture capital. Semester I: statistical analysis of detection/classification systems (receiver operation characteristic analysis, logistic regression), development of design prototype, need, approach, benefits and competition analysis. Semester II: spiral develop process and testing, iteration and refinement of the initial design/prototype and business plan development. A lab fee of $100 each is collected.
- TR 10:10 a.m.-11:25 a.m.
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Instructor:
Lauren N Heckelman
Info - 4 points
SPECIAL TOPICS IN BIOMEDICAL ENGINEERING
CellBioEng&Therapeutics
Current topics in biomedical engineering. Subject matter will vary by year.
SPECIAL TOPICS IN BIOMEDICAL ENGINEERING
Life Sci Future Entreps
Current topics in biomedical engineering. Subject matter will vary by year.
- W 1:10 p.m.-3:40 p.m.
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Instructor:
Millard Y Chan
Info - 3 points
QUANTITATIVE PHYSIOLOGY I
Physiological systems at the cellular and molecular level are examined in a highly quantitative context. Topics include chemical kinetics, molecular binding and enzymatic processes, molecular motors, biological membranes, and muscles.
- MW 8:40 a.m.-9:55 a.m.
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Instructor:
Lance Kam
CULPA: 7
h-index: 38
Info
- 3 points
BIOSTATISTICS FOR ENGINEERS
Fundamental concepts of probability and statistics applied to biology and medicine. Probability distributions, hypothesis testing and inference, summarizing data and testing for trends. Signal detection theory and the receiver operator characteristic. Lectures accompanied by data analysis assignments using MATLAB as well as discussion of case studies in biomedicine.
- TR 11:40 a.m.-12:55 p.m.
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Instructor:
Nuttida Rungratsameetaweemana
Info - 4 points
SOLID BIOMECHANICS
Applications of continuum mechanics to the understanding of various biological tissues properties. The structure, function, and mechanical properties of various tissues in biolgical systems, such as blood vessels, muscle, skin, brain tissue, bone, tendon, cartilage, ligaments, etc. are examined. The establishment of basic governing mechanical principles and constitutive relations for each tissue. Experimental determination of various tissue properties. Medical and clinical implications of tissue mechanical behavior.
- T 1:10 p.m.-3:40 p.m.
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Instructor:
X. Edward Guo
CULPA: 2 h-index: 70 Info - 3 points
PRIN OF ULTRASOUND IN MEDICINE
ULTRASOUND IN DIAGNOSTC IMAGNG
Fourier analysis. Physics of diagnostic ultrasound and principles of ultrasound imaging instrumentation. Propagation of plane waves in lossless medium; ultrasound propagation through biological tissues; single-element and array transducer design; pulse-echo and Doppler ultrasound instrumentation, performance evaluation of ultrasound imaging systems using tissue-mimicking phantoms, ultrasound tissue characterization; ultrasound nonlinearity and bubble activity; harmonic imaging; acoustic output of ultrasound systems; biological effects of ultrasound.
- W 2:30 p.m.-5 p.m.
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Instructor:
Elisa Konofagou
Wikipedia h-index: 71 Info - 3 points
Statistical machine learning for genomic
Statistical ML for genomi
Introduction to statistical machine learning methods using applications in genomic data and in particular high-dimensional single-cell data. Concepts of molecular biology relevant to genomic technologies, challenges of high-dimensional genomic data analysis, bioinformatics preprocessing pipelines, dimensionality reduction, unsupervised learning, clustering, probabilistic modeling, hidden Markov models, Gibbs sampling, deep neural networks, gene regulation. Programming assignments and final project will be required.
- R 10:10 a.m.-12:40 p.m.
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Instructor:
Elham Azizi
h-index: 10 Info - 3 points
Magnetic Resonance Spectroscopy: A Windo
Introduction to use of magnetic resonance spectroscopy (MRS) with focus on brain. Covers all aspects of in vivo MRS from theory to experiment, from data acquisition to the derivation of metabolic signatures, from study design to clinical interpretation. Includes theoretical concepts, hands-on training in MRS data literacy and direct experimental experience using a 3T MR scanner.
- R 4:10 p.m.-6:40 p.m.
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Instructor:
Christoph Juchem
CULPA: 1 h-index: 23 Info - 3 points
Functional Genomics: Methods and Applica
Introduces approaches for the functional genomic analysis of biological systems and their use to define genotype-phenotype relationships. Genetic variation, gene expression and regulation at the epigenome, chromatin organization level, and link between gene and protein expression covered. Case studies covered: study of cancer and cancer-associated processes, neuro-biology, and organismal development. The presented methods study these events at the genome, epigenome, transcriptome, and proteome levels.Approaches that increase the resolution of functional genomic assays to the level of individual cells, spatial profiling, integration with genetic and chemical screening methods, and their application to chemical genomic approaches also studied. Programming assignments and a final project required.
- T 1:10 p.m.-3:40 p.m.
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Instructor:
Jose McFaline-Figueroa
Info - 3 points
Biomaterials and Scaffold Design
An introduction to the strategies and fundamental bioengineering design criteria in the development of biomaterials and tissue ngineered grafts. Materials structuralfunctional relationships, biocompatibility in terms of material and host responses. Through discussions, readings, and a group design project, students acquire an understanding of cell-material interactions and identify the arameters critical in the design and selection of biomaterials for biomedical applications.
- T 1:10 p.m.-3:40 p.m.
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Instructor:
Helen Lu
CULPA: 1 h-index: 54 Info - 3 points
TISSUE ENGINEERING
An introduction to the strategies and fundamental bioengineering design criteria behind the development of cell-based tissue substitutes. Topics include biocompatibility, biological grafts, gene therapy-transfer, and bioreactors.
- MW 11:40 a.m.-12:55 p.m.
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Instructor:
Clark T Hung
CULPA: 5 h-index: 65 Info - 3 points
DRUG AND GENE DELIVERY
Application of polymers and other materials in drug and gene delivery, with focus on recent advances in field. Basic polymer science, pharmacokinetics, and biomaterials, cell-substrate interactions, drug delivery system fabrication from nanoparticles to microparticles and electrospun fibrous membranes. Applications include cancer therapy, immunotherapy, gene therapy, tissue engineering, and regenerative medicine. Course readings include textbook chapters and journal papers. Homework assignments take format of assay responding to open-ended question. Term paper and 30-minute PowerPoint presentation required at end of semester.
- M 1:10 p.m.-3:40 p.m.
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Instructor:
Kam W Leong
h-index: 126 Info - 3 points
SOUND AND HEARING
Introductory acoustics, basics of waves and discrete mechanical systems. The mechanics of hearing - how sound is transmitted through the external and middle ear to the inner ear, and the mechanical processing of sound within the inner ear.
- M 4:10 p.m.-6:40 p.m.
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Instructor:
Elizabeth Olson
h-index: 28 Info - 3 points
GRADUATE SPECIAL TOPIC
Instructive Biomaterials
Current topics in biomedical engineering. Subject matter will vary by year.
- W 1:10 p.m.-3:40 p.m.
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Instructor:
Treena L Arinzeh
Wikipedia Info - 3 points
GRADUATE SPECIAL TOPIC
Health as a System
Current topics in biomedical engineering. Subject matter will vary by year.
- W 10:10 a.m.-12:40 p.m.
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Instructor:
Henry Hess
CULPA: 1 h-index: 45 Info - 3 points
BIOMEDICAL ENGINEERING SEMINAR
All matriculated graduate students are required to attend the seminar as long as they are in residence. No degree credit is granted. The seminar is the principal medium of communication among those with biomedical engineering interests within the University. Guest speakers from other institutions, Columbia faculty, and students within the Department who are advanced in their studies frequently offer sessions.
- R 1:10 p.m.-2:25 p.m.
- 0 points