Introduction to Biomedical Engineering D
Intro to Biomedical Eng D
An introduction to prototyping techniques needed for medical device development, including computer-aided design (CAD), 3D printing, laser cutting, circuit design, and microcontrollers. Students will work collaboratively to design, fabricate, and evaluate a medical device, demonstrating competency in fabrication methods and iterative engineering design.
- TR 8:40 a.m.-9:55 a.m.
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Instructor:
Lauren N Heckelman
Info - 3 points
BIOMEDICAL ENGINEERING II
Various concepts within the field of biomedical engineering, foundational knowledge of engineering methodology applied to biological and/or medical problems through modules in biomechanics, bioinstrumentation, and biomedical imaging.
- MW 10:10 a.m.-11:25 a.m.
- 3 points
BIOMEDICAL ENGINEERING LAB II
Biomedical experimental design and hypothesis testing. Statistical analysis of experimental measurements. Analysis of experimental measurements. Analysis of variance, post hoc testing. Fluid shear and cell adhesion, neuro-electrophysiology, soft tissue biomechanics, biomecial imaging and ultrasound, characterization of excitable tissues, microfluidics.
- R 1:10 p.m.-3:45 p.m.
- W 1:10 p.m.-3:45 p.m.
- 3 points
BIOMEDICAL ENGIN DESIGN II
A two-semester design sequence to be taken in the senior year. Elements of the design process, with specific applications to biomedical engineering: concept formulation, systems synthesis, design analysis, optimization, biocompatibility, impact on patient health and comfort, health care costs, regulatory issues, and medical ethics. Selection and execution of a project involving the design of an actual engineering device or system. Introduction to entrepreneurship, biomedical start-ups, and venture capital. Semester I: statistical analysis of detection/classification systems (receiver operation characteristic analysis, logistic regression), development of design prototype, need, approach, benefits and competition analysis. Semester II: spiral develop process and testing, iteration and refinement of the initial design/prototype and business plan development. A lab fee of $100 each is collected.
- TR 10:10 a.m.-11:25 a.m.
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Instructor:
Lauren N Heckelman
Info - 4 points
PROJECTS IN BIOMEDICAL ENGIN
Projects in Biomedical Enginee
Independent projects involving experimental, theoretical, computational, or engineering design work. May be repeated, but no more than 3 points of this or any other projects or research course may be counted toward the technical elective degree requirements as engineering technical electives.
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Instructor:
Lauren N Heckelman
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Instructor:
Tal Danino
Wikipedia h-index: 18 Info -
Instructor:
X. Edward Guo
CULPA: 2 h-index: 70 Info -
Instructor:
Henry Hess
CULPA: 1 h-index: 45 Info -
Instructor:
Clark T Hung
CULPA: 5 h-index: 65 Info -
Instructor:
Lance Kam
CULPA: 7
h-index: 38
Info
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Instructor:
Elisa Konofagou
Wikipedia h-index: 71 Info -
Instructor:
Andrew Laine
Wikipedia h-index: 43 Info -
Instructor:
Kam W Leong
h-index: 126 Info -
Instructor:
Helen Lu
CULPA: 1 h-index: 54 Info -
Instructor:
Barclay Morrison
CULPA: 9 h-index: 42 Info -
Instructor:
Paul Sajda
CULPA: 3 h-index: 47 Info -
Instructor:
Samuel Sia
CULPA: 1 h-index: 39 Info -
Instructor:
Gordana Vunjak-Novakovic
Wikipedia h-index: 132 Info -
Instructor:
Qi Wang
h-index: 24 Info -
Instructor:
Nandan L Nerurkar
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Instructor:
Elham Azizi
h-index: 10 Info -
Instructor:
Jose McFaline-Figueroa
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Instructor:
Treena L Arinzeh
Wikipedia Info -
Instructor:
Santiago Correa
Info - 1-3 points
PROJECTS IN BIOMEDICAL ENGIN
Projects in Biomedical Enginee
Independent projects involving experimental, theoretical, computational, or engineering design work. May be repeated, but no more than 3 points of this or any other projects or research course may be counted toward the technical elective degree requirements as engineering technical electives.
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Instructor:
Santiago Correa
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Instructor:
Grace McIlvain
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Instructor:
Ke Cheng
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Instructor:
Parisa Yousefpour
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Instructor:
Sanja Vickovic
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Instructor:
John T Vaughan
Info - 1-3 points
UNDERGRADUATE FIELDWORK
May be repeated for credit, but no more than 3 total points may be used toward the 128-credit degree requirement. Only for BMEN undergraduate students who include relevant off-campus work experience as part of their approved program of study. Final report and letter of evaluation required. Fieldwork credits may not count toward any major core, technical, elective, and non-technical requirements. May not be taken for pass/fail credit or audited. International students must also consult with the International Students and Scholars Office.
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Instructor:
Lauren N Heckelman
Info - 1-2 points
SPECIAL TOPICS IN BIOMEDICAL ENGINEERING
Comp Neuro Dyn Cross Spec
Current topics in biomedical engineering. Subject matter will vary by year.
- W 4:10 p.m.-6:30 p.m.
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Instructor:
Nuttida Rungratsameetaweemana
Info - 3 points
SPECIAL TOPICS IN BIOMEDICAL ENGINEERING
Spec Topics: SynBio
Current topics in biomedical engineering. Subject matter will vary by year.
- R 1:10 p.m.-3:40 p.m.
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Instructor:
Tal Danino
Wikipedia h-index: 18 Info - 3 points
SPECIAL TOPICS IN BIOMEDICAL ENGINEERING
Cell & Gene Therapy D3
Current topics in biomedical engineering. Subject matter will vary by year.
QUANT PHYSIOLOGY II:ORGAN SYST
Students are introduced to a quantitative, engineering approach to cellular biology and mammalian physiology. Beginning with biological issues related to the cell, the course progresses to considerations of the major physiological systems of the human body (nervous, circulatory, respiratory, renal).
- MW 8:40 a.m.-9:55 a.m.
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Instructor:
Barclay Morrison
CULPA: 9 h-index: 42 Info - 3 points
FLUID BIOMECHANICS
The principles of continuum mechanics as applied to biological fluid flows and transport. Continuum formulations of basic conservation laws, Navier-Stokes equations, mechanics of arterial and venous blood flow, blood rheology and non-Newtonian properties, flow and transport in the microcirculation, oxygen diffusion, capillary filtration.
- T 4:10 p.m.-6:40 p.m.
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Instructor:
X. Edward Guo
CULPA: 2 h-index: 70 Info - 3 points
Biomechanics of Developmental Biology
BIOMECHANICS DEVELOPMENTA
Biophysical mechanisms of tissue organization
during embryonic development: conservation laws, reaction-diffusion, finite elasticity, and fluid mechanics are reviewed and applied to a broad range of topics in developmental biology, from early development to later organogenesis of the central nervous, cardiovascular, musculoskeletal, respiratory, and gastrointestinal systems. Subdivided into modules on patterning (conversion of diffusible cues into cell fates) and morphogenesis (shaping of tissues), the course will include lectures, problem sets, reading of primary literature, and a final project.
- MW 1:10 p.m.-2:25 p.m.
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Instructor:
Nandan L Nerurkar
Info - 3 points
PRIN OF ULTRASOUND IN MEDICINE
ULTRASOUND IN DIAGNOSTC IMAGNG
Fourier analysis. Physics of diagnostic ultrasound and principles of ultrasound imaging instrumentation. Propagation of plane waves in lossless medium; ultrasound propagation through biological tissues; single-element and array transducer design; pulse-echo and Doppler ultrasound instrumentation, performance evaluation of ultrasound imaging systems using tissue-mimicking phantoms, ultrasound tissue characterization; ultrasound nonlinearity and bubble activity; harmonic imaging; acoustic output of ultrasound systems; biological effects of ultrasound.
- W 4:10 p.m.-6:40 p.m.
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Instructor:
Elisa Konofagou
Wikipedia h-index: 71 Info - 3 points
PRIN OF MAG RESONANCE IMAGING
Fundamental principles of Magnetic Resonance Imaging (MRI), including the underlying spin physics and mathematics of image formation with an emphasis on the application of MRI to neuroimaging, both anatomical and functional. The examines both theory and experimental design techniques.
- R 4:10 p.m.-6:40 p.m.
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Instructor:
John T Vaughan
Info - 3 points
Deep Learning in Biomedical Imaging
Deep Learning in BME / Im
Introduction to methods in deep learning, with focus on applications to quantitative problems in biomedical imaging and Artificial Intelligence (AI) in medicine. Network models: Deep feedforward networks, convolutional neural networks and recurrent neural networks. Deep autoencoders for denoising. Segmentation and classification of biological tissues and biomarkers of disease. Theory and methods lectures will be accompanied with examples from biomedical image including analysis of neurological images of the brain (MRI), CT images of the lung for cancer and COPD, cardiac ultrasound. Programming assignments will use tensorflow / Pytorch and Jupyter Notebook. Examinations and a final project will also be required.
Advanced Cell and Tissue Engineering: Fr
Advanced Cell & Tis Eng:
Covers advancements in the fields of cellular and developmental biology, molecular biology and materials science towards the development of “tissue engineered” therapies. Emphasis on tissue engineering therapies applied to musculoskeletal tissues, such as bone, cartilage, and skeletal muscle, and nervous tissues (central and peripheral nervous system). Design considerations and concepts in market analysis examined.
- R 4:10 p.m.-6:40 p.m.
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Instructor:
Treena L Arinzeh
Wikipedia Info - 3 points
Immunoengineering with Biomaterials and
ImmunoEng with Biomat&Nan
Introduction to fundamental aspects of immunology and engineering strategies to modulate the immune system to improve human health. We will cover the innate and adaptive immune system and current methods to characterize the immune response. Applications focus on cancer, vaccines, and autoimmune disorders.
- MW 11:40 a.m.-12:55 p.m.
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Instructor:
Santiago Correa
Info - 3 points
Multimodal Neuroimaging
Practical implementation of neuroimaging techniques, data types, processing methods and clinical findings on independent datasets across a variety of neurological and psychiatric conditions. Basics from anatomy to digital image analysis will be explored culminating in a final project.
- R 4:10 p.m.-6:40 p.m.
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Instructor:
Frank A Provenzano
Info - 0-3 points
MICRO/NANO STRUCT CELL ENG
Design, fabrication, and application of micro-/nanostructured systems for cell engineering. Recognition and response of cells to spatial aspects of their extracellular environment. Focus on neural, cardiac, coculture, and stem cell systems. Molecular complexes at the nanoscale.
- M 2:10 p.m.-4 p.m.
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Instructor:
Lance Kam
CULPA: 7
h-index: 38
Info
- 3 points
High-dimensional statistics for biomedic
HD Stat for biomedical da
Statistical machine learning techniques and advanced mathematical concepts for analysis of high-dimensional biomedical data. Topics include optimal transport and probabilistic modeling for multi-modal genomic and imaging data integration and analysis of spatial and temporal dynamics. Programming assignments, problem sets, and a final project will be required.
- R 10:10 a.m.-12:40 p.m.
- 3 points
Biomolecular Engineering: Principles and
This course provides an integrated lecture–laboratory introduction to modern biomolecular engineering and molecular biology techniques used in biotechnology and biomedical research. Students will gain a foundational understanding of how genetic information is stored, replicated, expressed, and engineered, as well as hands-on experience with core experimental techniques used in the field.
Students are required to complete the required lab safety trainings prior to the first lab (instructions will be provided by the instructor), and attend all lab sessions. Lecture slides will be posted on CourseWorks; students are responsible for all material covered in class.
- T 1:10 p.m.-3:40 p.m.
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Instructor:
Parisa Yousefpour
Info - 3 points
BIOMEMS:CELL/MOLECULAR APPLIC
Topics include biomicroelectromechanical, microfluidic, and lab-on-a-chip systems in biomedical engineering, with a focus on cellular and molecular applications. Microfabrication techniques, biocompatibility, miniaturization of analytical and diagnostic devices, high-throughput cellular studies, microfabrication for tissue engineering, and in vivo devices.
- W 4:10 p.m.-6:40 p.m.
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Instructor:
Samuel Sia
CULPA: 1 h-index: 39 Info - 3 points
FIELDWORK
Only for BMEN graduate students who need relevant work experience as part of their program of study. Final reports required. May not be taken for pass/fail credit or audited. International students must also consult with the International Students and Scholars Office.
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Instructor:
Clark T Hung
CULPA: 5 h-index: 65 Info - 1-2 points
COMP MODELING-PHYSIOL SYSTEMS
Advanced computational modeling and quantitative analysis of selected physiological systems from molecules to organs. Selected systems are analyzed in depth with an emphasis on modeling methods and quantitative analysis. Topics may include cell signaling, molecular transport, excitable membranes, respiratory physiology, nerve transmission, circulatory control, auditory signal processing, muscle physiology, data collection and analysis.
- M 4:10 p.m.-6:40 p.m.
- 3 points
BIOMEDICAL INNOVATION I
Project-based design experience for graduate students. Elements of design process, including need identification, concept generation, concept selection, and implementation. Development of design prototype and introduction to entrepreneurship and implementation strategies. Real-world training in biomedical design and innovation.
- MW 2:10 p.m.-4 p.m.
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Instructor:
Megan Heenan
Info - 3 points
LAB-TO-MARKET
Introduction to and application of commercialization of biomedical innovations. Topics include needs clarification, stakeholder analysis, market analysis, value proposition, business models, intellectual property, regulatory, and reimbursement. Development of path-to-market strategy and pitch techniques.
- R 4:10 p.m.-7:25 p.m.
- 3 points
STEM CELL, GENOME ENG & REGEN MED
General lectures on stem cell biology followed by student presentations and discussion of the primary literature. Themes presented include: basic stem cell concepts; basic cell and molecular biological characterization of endogenous stem cell populations; concepts related to reprogramming; directed differentiation of stem cell populations; use of stem cells in disease modeling or tissue replacement/repair; clinical translation of stem cell research.
- T 9 a.m.-11 a.m.
- 3 points
Engineering in Genomics & AI
Modern “omics” methods comprise a set of high-throughput techniques useful for the study of entire sets of biological molecules, such as genomes, transcripts, and proteins. These approaches strive to provide a comprehensive view of a living system, and are increasingly used to probe cellular diversity, trace the evolution and spread of pathology, and to directly connect molecules to functional changes at the level of the cell or organism. This course will survey the foundational technologies and ideas underpinning such work by building a clear, intuitive understanding of modern methods—sequencing chemistries (Illumina, PacBio HiFi, ONT), single-cell and spatial transcriptomics, single-cell and spatial DNA sequencing, in situ imaging-based sequencing, genome editing, and CRISPR-based perturbations—with computational themes like base-calling, normalization, cell-type classification, and interpretation of perturbation data. Familiarity with basic genomics methods and processing of biological data is helpful but not required.
- F 1 p.m.-3 p.m.
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Instructor:
Sanja Vickovic
Info - 3 points
MASTERS RESEARCH
Candidates for the M.S. degree may conduct an investigation of some problem in biomedical engineering. No more than 6 points in this course may be counted for graduate credit.
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Instructor:
Clark T Hung
CULPA: 5 h-index: 65 Info -
Instructor:
Tal Danino
Wikipedia h-index: 18 Info -
Instructor:
X. Edward Guo
CULPA: 2 h-index: 70 Info -
Instructor:
Henry Hess
CULPA: 1 h-index: 45 Info -
Instructor:
Lance Kam
CULPA: 7
h-index: 38
Info
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Instructor:
Elisa Konofagou
Wikipedia h-index: 71 Info -
Instructor:
Andrew Laine
Wikipedia h-index: 43 Info -
Instructor:
Kam W Leong
h-index: 126 Info -
Instructor:
Helen Lu
CULPA: 1 h-index: 54 Info -
Instructor:
Barclay Morrison
CULPA: 9 h-index: 42 Info -
Instructor:
Elizabeth Olson
h-index: 28 Info -
Instructor:
Paul Sajda
CULPA: 3 h-index: 47 Info -
Instructor:
Kenneth Shepard
CULPA: 2 Wikipedia h-index: 64 Info -
Instructor:
Samuel Sia
CULPA: 1 h-index: 39 Info -
Instructor:
Stavros Thomopoulos
h-index: 63 Info -
Instructor:
John T Vaughan
Info -
Instructor:
Qi Wang
h-index: 24 Info -
Instructor:
Nandan L Nerurkar
Info -
Instructor:
Stephen H Tsang
Wikipedia h-index: 58 Info -
Instructor:
Elham Azizi
h-index: 10 Info -
Instructor:
Jose McFaline-Figueroa
Info -
Instructor:
Treena L Arinzeh
Wikipedia Info -
Instructor:
Sanja Vickovic
Info -
Instructor:
Santiago Correa
Info -
Instructor:
Kaveri A Thakoor
Info -
Instructor:
Yasmine El-Shamayleh
Info -
Instructor:
Alice H Huang
Info -
Instructor:
Ke Cheng
Info -
Instructor:
Grace McIlvain
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Instructor:
Despina Kontos
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Instructor:
Nadeen O Chahine
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Instructor:
Parisa Yousefpour
Info - 1-6 points
Master's Thesis in BME
This is a Pass/Fail zero credit course, “BME Master's Thesis” for MS students who are in the process of doing a thesis (BMEN E9100). It would be registered for before/during the final semester, the semester when the student will be defending the thesis. It must be approved by the faculty mentor.
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Instructor:
Clark T Hung
CULPA: 5 h-index: 65 Info -
Instructor:
Elizabeth Olson
h-index: 28 Info - 0 points
DOCTORAL RESEARCH
Doctoral candidates are required to make an original investigation of a problem in biomedical engineering, the results of which are presented in the dissertation.
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Instructor:
Gerard A Ateshian
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Instructor:
Tal Danino
Wikipedia h-index: 18 Info -
Instructor:
X. Edward Guo
CULPA: 2 h-index: 70 Info -
Instructor:
Clark T Hung
CULPA: 5 h-index: 65 Info -
Instructor:
Lance Kam
CULPA: 7
h-index: 38
Info
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Instructor:
Elisa Konofagou
Wikipedia h-index: 71 Info -
Instructor:
Andrew Laine
Wikipedia h-index: 43 Info -
Instructor:
Kam W Leong
h-index: 126 Info -
Instructor:
Helen Lu
CULPA: 1 h-index: 54 Info -
Instructor:
Barclay Morrison
CULPA: 9 h-index: 42 Info -
Instructor:
Elizabeth Olson
h-index: 28 Info -
Instructor:
Paul Sajda
CULPA: 3 h-index: 47 Info - 1-6 points