Detailed introduction to cellular and subcellular biology: cell structures and functions, energy metabolism, biogenesis of cell components, biology of inheritance, molecular genetics, regulation of gene expression, and genes in development.
A laboratory-based introduction to cell and molecular biology. Both classic and modern approaches are used to investigate principles of heredity as well as the structure and function of cells and their molecular components. Lab exercises introduce practical techniques and data analysis.
A laboratory-based introduction to cell and molecular biology. Both classic and modern approaches are used to investigate principles of heredity as well as the structure and function of cells and their molecular components. Lab exercises introduce practical techniques and data analysis.
A laboratory-based introduction to cell and molecular biology. Both classic and modern approaches are used to investigate principles of heredity as well as the structure and function of cells and their molecular components. Lab exercises introduce practical techniques and data analysis.
A laboratory-based introduction to cell and molecular biology. Both classic and modern approaches are used to investigate principles of heredity as well as the structure and function of cells and their molecular components. Lab exercises introduce practical techniques and data analysis.
A laboratory-based introduction to cell and molecular biology. Both classic and modern approaches are used to investigate principles of heredity as well as the structure and function of cells and their molecular components. Lab exercises introduce practical techniques and data analysis.
A laboratory-based introduction to cell and molecular biology. Both classic and modern approaches are used to investigate principles of heredity as well as the structure and function of cells and their molecular components. Lab exercises introduce practical techniques and data analysis.
A laboratory-based introduction to cell and molecular biology. Both classic and modern approaches are used to investigate principles of heredity as well as the structure and function of cells and their molecular components. Lab exercises introduce practical techniques and data analysis.
A laboratory-based introduction to cell and molecular biology. Both classic and modern approaches are used to investigate principles of heredity as well as the structure and function of cells and their molecular components. Lab exercises introduce practical techniques and data analysis.
A laboratory-based introduction to cell and molecular biology. Both classic and modern approaches are used to investigate principles of heredity as well as the structure and function of cells and their molecular components. Lab exercises introduce practical techniques and data analysis.
A laboratory-based introduction to cell and molecular biology. Both classic and modern approaches are used to investigate principles of heredity as well as the structure and function of cells and their molecular components. Lab exercises introduce practical techniques and data analysis.
A laboratory-based introduction to cell and molecular biology. Both classic and modern approaches are used to investigate principles of heredity as well as the structure and function of cells and their molecular components. Lab exercises introduce practical techniques and data analysis.
Prerequisites: ) Limited to 16 students who are participating in the Science Pathways Scholars Program. Students in this seminar course will be introduced to the scientific literature by reading a mix of classic papers and papers that describe significant new developments in the field. Seminar periods will be devoted to oral reports, discussion of assigned reading, and student responses. Section 1: Limited to students in the Science Pathways Scholars Program. Section 2: Limited to first-year students who received a 4 or 5 on the AP and are currently enrolled in BIOL BC1500.
Mendelian and molecular genetics of both eukaryotes and prokaryotes, with an emphasis on human genetics. Topics include segregation, recombination and linkage maps, cytogenetics, gene structure and function, mutation, molecular aspects of gene expression and regulation, genetic components of cancer, and genome studies.
Prerequisites: BIOL BC1500, BIOL BC1501, BIOL BC1502, BIOL BC1503 or the equivalent. Survey of plant biology emphasizing evolutionary and ecological perspectives on mating and reproduction, physiology, anatomy, and morphology.
The definition of ecological problems in experimentally tractable ways; the design of experiments and analysis of ecological data; class projects on population ecology. Students conduct individual projects during last month of term.
Prerequisites: BIOL BC1500, BIOL BC1501, BIOL BC1502, BIOL BC1503 or equivalent. This introduction to animal behavior takes an integrative approach to understand the physiological and genetic basis of behavior, the ecological context of behavior, and the evolutionary consequences of behavior. This course focuses on the process of scientific research, including current research approaches in animal behavior and practical applications of these findings.
An introduction to the basics of Python and R coding in the context of solving basic problems in molecular biology. Python will be used to write programs that analyze various features of DNA sequence data and R will be used to analyze output from RNA-seq experiments. No prior programming experience is necessary. The work will involve modifying existing code as well as developing simple programs from the ground up.
Learning objectives:
This course will provide a comprehensive foundation in programming methodology for quantitative biology applications that can be readily applied to any programming language. It is recommended for students interested in establishing or expanding their computational biology skillset. After completing this course, students should be able to:
1. Understand and explain the role of numerical and statistical methods in biology
2. Execute numerical computations using a widely-used programming language
3. Recognize common programming motifs that can be readily applied to other widely used languages
4. Design and troubleshoot algorithms to analyze diverse biological data and implement them using functions and scripts
5. Apply statistical programming techniques to model biological systems
6. Generate and interpret diverse plots based on biological datasets
Course overview:
Once a small subfield of biology, computational biology has evolved into a massive field of its own, with computational methods fast becoming a vital toolkit leveraged by biologists across the discipline. As the size and complexity of biological datasets grows, computational methods allow scientists to make sense of these data, scaling quantitative methods to extract meaningful insights that help us better understand ourselves and the living world around us. In this course, we will learn the basics of computer programming in R, a powerful programming language with wide use in the biological sciences. Topics will include a basic introduction to R and the RStudio environment, data types and control structures, reading and writing files in R, data processing and visualization, manipulating common biological datasets; and statistical testing and modeling in R.
This course serves as a continuation of BIOL2500 R for Scientists. The course will meet weekly. Students will explore a range of methods and resources used by contemporary computational biologists. These include advanced statistical modeling approaches, manipulating genomic and spatial data, and working in R outside of the RStudio environment (including git, bash, Shiny and high-performance computing). Students will have opportunities to explore diverse biological and statistical R packages in the context of homework assignments, and will analyze a dataset of their own choosing for a semester project.
Selected topics in molecular genetics and gene regulation, with a focus on examples from human evolution, physiology, and disease. The course will be organized into four modules with combined lecture and journal club-style discussion. Module topics include molecular regulation of transcription, epigenetic regulation of the genome, gene regulatory networks, and genome architecture and evolution. We will draw from examples in the current literature and explore current experimental approaches in molecular genetics of humans and model organisms.
Laboratory course in which students conduct original research projects in molecular genetics. Students will participate in experimental design, conduct data analysis, and work with key techniques for studying gene structure, expression, and function including nucleic acid extraction and synthesis, cloning, bioinformatics analysis, PCR, and qPCR. Students will present their results orally and in writing. Enrollment in both semesters (BIOL BC3305 and BIOL BC3306) of this full-year course is required, and fulfills two upper-level lab courses for the Barnard Biology major. Must be taken in sequence, beginning in the fall.
Prerequisites: BIOL BC1500, BIOL BC1501, BIOL BC1502, BIOL BC1503 or the equivalent, and BIOL BC2100. Survey of the diversity, cellular organization, physiology, and genetics of the major microbial groups. Also includes aspects of applied microbiology and biotechnology, the function of microorganisms in the environment, and the role of microbes in human diseases.
Enrollment limited to 16. Provides experience in the isolation, cultivation, and analysis of pure cultures of microorganisms. Methods used for the study of cell structure, growth, physiology, and genetics of microbes will be incorporated into laboratory exercises.
This is an advanced seminar course focusing on primary literature studying viruses and their impact on public health. Selected topics will emphasize evolution, transmission, surveillance, and treatment. The intellectual framework will progress from the cellular and molecular levels to the organismal and ecological. Host-pathogen interactions between viruses and humans will be a particular focus. The course is organized around presentation and critique of both current research as well as landmark discoveries in the field. Discussions will also integrate the interplay of laboratory science with ethics and policy.
This lab course will explore the foundational methods of vertebrate embryology. Using both classical and modern experimental approaches, we will identify and manipulate developmental processes such as gastrulation, neurulation, and organogenesis. Students will investigate molecular regulation of patterning and the importance of tissue-tissue interactions during early development. Utilizing modern genetic tools and imaging techiniques, such as digital microscopy, students will have the opportunity to visualize embyrogenesis in real-time.
Prerequisite: Two terms of introductory biology (BIOL BC1500,BC1502 or equivalent) AND one term of Genetics (BIOL BC2100 or equivalent) AND at least one upper level lab course at the cell and molecular level. OR permission from the instructor.
This course will explore developing topics in reproductive biology, with a focus on mammalian reproduction. Using primary literature sources we will explore the molecular and physiological nature of reproduction, including fertilization, assisted reproductive technologies, and physiological changes to the reproductive system during and after birth. These topics will be further discussed in the context of medicine and society, with a particular focus on healthcare disparities in local communities.
Prerequisites: Pre- (or co-) requisite is a physiology lecture class (e.g. BIOL BC3360). Enrollment limited to 16. Provides a hands-on introduction to the different physiological systems in vertebrates and invertebrates. Emphasizes the operation of a variety of physiological monitoring devices and the collection and analysis of physiological data.
Vertebrates have been around for millions of years. In that time, they have evolved morphological attributes to live in the sea, on land, and in the air; hunt or scavenge food; escape from predation; and more. Yet despite the vast differences that have evolved, vertebrates (including humans) share many common traits. In this course, we will explore the evolution of the vertebrate body plan, focusing specifically on the evolution of form and function in many body systems. We will examine the evolution of homologous structures and identify how vertebrates have evolved a wide array of adaptations within the constraints of evolution. Though anatomy courses necessitate memorization of some key structures, we will focus more on the function of those structure, the broad principles of evolution, and the research techniques used in the related field of functional morphology rather than memorizing large lists of terms.
Required for all majors who do not select the year-long Senior Thesis Research & Seminar (BIOL BC3593 & BC3594) to fulfill their senior capstone requirement. These seminars allow students to explore the primary literature in the Biological Sciences in greater depth than can be achieved in a lecture course. Attention will be focused on both theoretical and empirical work. Seminar periods are devoted to oral reports and discussion of assigned readings and student reports. Students will write one extensive literature review of a topic related to the central theme of the seminar section.
Topics vary per semester and include, but are not limited to:
Plant Development
,
Animal Development & Evolution,
Molecular Evolution, Microbiology & Global Change, Genomics, Comparative & Reproductive Endocrinology, and Data Intensive Approaches in Biology.
This year-long course is open to junior and senior Biology majors and minors. Students will complete an independent research project in Biology under the guidance of a faculty mentor at Barnard or another local institution. Attendance at the weekly seminar is required. By the end of the year, students will write a scientific paper about their project and give a poster presentation about their research at the Barnard Biology Research Symposium.
Completion of this year-long course fulfills two upper-level laboratory requirements for the Biology major or minor. This course must be taken in sequence, beginning with BIOL BC3591 in the Fall and continuing with BIOL BC3592 in the Spring. Acceptance into this course requires confirmation of the research project by the course instructors. A Barnard internal mentor is required if the research project is not supervised by a Barnard faculty member. This course cannot be taken at the same time as BIOL BC3593-BIOL BC3594.
This year-long course is open to junior and senior Biology majors and minors. Students will complete an independent research project in Biology under the guidance of a faculty mentor at Barnard or another local institution. Attendance at the weekly seminar is required. By the end of the year, students will write a scientific paper about their project and give a poster presentation about their research at the Barnard Biology Research Symposium.
Completion of this year-long course fulfills two upper-level laboratory requirements for the Biology major or minor. This course must be taken in sequence, beginning with BIOL BC3591 in the Fall and continuing with BIOL BC3592 in the Spring. Acceptance into this course requires confirmation of the research project by the course instructors. A Barnard internal mentor is required if the research project is not supervised by a Barnard faculty member. This course cannot be taken at the same time as BIOL BC3593-BIOL BC3594.
This year-long course is open to senior Biology majors. Students will complete an independent research project in Biology under the guidance of a faculty mentor at Barnard or another local institution. Attendance at the weekly seminar is required. By the end of the year, students will write a scientific paper about their project and give an oral presentation about their research at the Barnard Biology Research Symposium.
Completion of this year-long course fulfills the senior capstone requirement for the Biology major. This course must be taken in sequence, beginning with BIOL BC3593 in the Fall and continuing with BIOL BC3594 in the Spring. Acceptance into this course requires confirmation of the research project by the course instructors. A Barnard internal mentor is required if the research project is not supervised by a Barnard faculty member. This course cannot be taken at the same time as BIOL BC3591-BIOL BC3592.
Similar to BIOL BC3591-BIOL BC3592, this is a one-semester course that provides students with degree credit for unpaid research
without
a seminar component. You may enroll in BIOL BC3597 for between 1-4 credits per semester. As a rule of thumb, you should be spending approximately 3 hours per week per credit on your research project.
A
Project Approval Form
must be submitted to the department each semester that you enroll in this course. Your Barnard research mentor (if your lab is at Barnard) or internal adviser in the Biology Department (if your lab is elsewhere) must approve your planned research
before
you enroll in BIOL BC3597. You should sign up for your mentor's section.
This course does not fulfill any Biology major requirements. It is open to students beginning in their first year.