Exploration of the major discoveries and ideas that have revolutionized the way we view organisms and understand life. This is an introductory survey course that explores basic concepts of molecular and cellular biology, genetics and evolution. Students will focus on biological concepts, biotechnology and bioethics, which inundate contemporary society.
Co-requisite: (strongly recommended) BIOL BC1501
This course is suitable for majors & fulfillment of pre-health requirements. A high school biology background or equivalent preparation is highly recommended.
BIOL BC1500 & BIOL BC1502 form a 2-semester introductory biology series and do not have to be taken in a fall to spring sequence.
Detailed introduction to biological phenomena above the cellular level; development, anatomy, and physiology of plants and animals; physiological, population, behavioral, and community ecology; evolutionary theory; analysis of micro-evolutionary events; and systematics.
A laboratory-based introduction to the major groups of living organisms; anatomy, physiology, evolution, and systematics; and laboratory techniques for studying and comparing functional adaptations.
A laboratory-based introduction to the major groups of living organisms; anatomy, physiology, evolution, and systematics; and laboratory techniques for studying and comparing functional adaptations.
A laboratory-based introduction to the major groups of living organisms; anatomy, physiology, evolution, and systematics; and laboratory techniques for studying and comparing functional adaptations.
A laboratory-based introduction to the major groups of living organisms; anatomy, physiology, evolution, and systematics; and laboratory techniques for studying and comparing functional adaptations.
A laboratory-based introduction to the major groups of living organisms; anatomy, physiology, evolution, and systematics; and laboratory techniques for studying and comparing functional adaptations.
A laboratory-based introduction to the major groups of living organisms; anatomy, physiology, evolution, and systematics; and laboratory techniques for studying and comparing functional adaptations.
A laboratory-based introduction to the major groups of living organisms; anatomy, physiology, evolution, and systematics; and laboratory techniques for studying and comparing functional adaptations.
A laboratory-based introduction to the major groups of living organisms; anatomy, physiology, evolution, and systematics; and laboratory techniques for studying and comparing functional adaptations.
Prerequisites: BIOL BC1001 or equivalent preparation. Enrollment limited to 16 students per section. Course suitable for fulfillment of premedical requirements. BIOL BC1500 as prerequisite or corequisite. A laboratory-based introduction to the major groups of living organisms; anatomy, physiology, evolution, and systematics; and laboratory techniques for studying and comparing functional adaptations.
Prerequisites: ) Limited to 16 students who are participating in the Science Pathways Scholars Program. Students in this seminar course will be introduced to the scientific literature by reading a mix of classic papers and papers that describe significant new developments in the field. Seminar periods will be devoted to oral reports, discussion of assigned reading, and student responses. Section 1: Limited to students in the Science Pathways Scholars Program. Section 2: Limited to first-year students who received a 4 or 5 on the AP and are currently enrolled in BIOL BC1500.
Mendelian and molecular genetics of both eukaryotes and prokaryotes, with an emphasis on human genetics. Topics include segregation, recombination and linkage maps, cytogenetics, gene structure and function, mutation, molecular aspects of gene expression and regulation, genetic components of cancer, and genome studies.
Prerequisites: (BIOL BC1500) and (BIOL BC1502) and (BIOL BC2280) and (BIOL BC1501) and (BIOL BC1503) This lab provides an introduction to animal behavior research, including current research approaches and practical applications of these findings. Students will complete two main projects. The first is a group project using the fruit fly, Drosophila melanogaster, which will involve observing, recording, and analyzing reproductive behaviors. The second is an independent project that will be designed, conducted, and analyzed by students using publicly available animal behavior resources and/or data. Both projects will incorporate critical thinking, problem solving and experimental design, with an emphasize on scientific writing and oral presentation skills.
Learning objectives:
This course will provide a comprehensive foundation in programming methodology for quantitative biology applications that can be readily applied to any programming language. It is recommended for students interested in establishing or expanding their computational biology skillset. After completing this course, students should be able to:
1. Understand and explain the role of numerical and statistical methods in biology
2. Execute numerical computations using a widely-used programming language
3. Recognize common programming motifs that can be readily applied to other widely used languages
4. Design and troubleshoot algorithms to analyze diverse biological data and implement them using functions and scripts
5. Apply statistical programming techniques to model biological systems
6. Generate and interpret diverse plots based on biological datasets
Course overview:
Once a small subfield of biology, computational biology has evolved into a massive field of its own, with computational methods fast becoming a vital toolkit leveraged by biologists across the discipline. As the size and complexity of biological datasets grows, computational methods allow scientists to make sense of these data, scaling quantitative methods to extract meaningful insights that help us better understand ourselves and the living world around us. In this course, we will learn the basics of computer programming in R, a powerful programming language with wide use in the biological sciences. Topics will include a basic introduction to R and the RStudio environment, data types and control structures, reading and writing files in R, data processing and visualization, manipulating common biological datasets; and statistical testing and modeling in R.
Corequisites: DNCE BC2573 This new interdisciplinary laboratory course will introduce students to the practices of creative and scientific research in anatomy. The laboratory course will offer students “hands-on” opportunities to view cadaveric specimens, to collect, analyze and communicate scientific information/data related to anatomy and to explore the use of anatomical information to generate creative movement and choreography.
Prerequisites: BIOL BC1500,1501, 1502, 1503 and BIOL BC2100, or equivalent.
Transcriptome analysis, or the analysis of all expressed RNA sequences in a cell, has long been a major part of molecular biology and genetics. The modern technique of RNA-Seq has now been established as the approach for transcriptome studies and RNA-Seq analyses are ubiquitous in all areas of Biology. In this course we will cover the major technical and analytical aspects of RNA-Seq with an emphasis on the application by students to real datasets. We will cover both the original ‘Bulk RNA-Seq’ approach, where the total transcriptome of many cells are combined, and the more recent ‘single-cell RNA-Seq’ (scRNA-Seq) technology where transcriptomes of individual cells are analyzed separately. Students will learn to read and interpret journal articles that utilize RNA-Seq datasets, both bulk and single-cell, and to perform and present RNA-Seq data using publicly available datasets.
Introduction to the use of molecular techniques to answer questions about subcellular biological phenomena. Techniques include isolation of genomic and plasmid DNAs, restriction enzyme analysis, DNA and protein electrophoresis, bacterial transformation, and plasmid subcloning.
Prerequisites: BIOL BC1500, BIOL BC1501, BIOL BC1502, BIOL BC1503, and BIOL BC2100 or permission of instructor. Enrollment limited to 16. Laboratory course in which students conduct original research projects in molecular genetics. Students will participate in experimental design, conduct and data analysis, and work with key techniques for studying gene structure, expression and function such as nucleic acid extraction and synthesis, cloning, bioinformatics analysis, PCR and qPCR. Students will present their results orally and in writing. Enrollment in both semesters (BIOL BC3305 and BIOL BC3306) of this full-year course is required, and fulfills two upper-level lab courses for the Barnard Biology major. Must be taken in sequence, beginning in the fall. -B. Morton - J. Mansfield
This course explores the components, systems, and regulatory mechanisms involved in eukaryotic cellular function. Topics include: signal transduction, translational and protein quality control, organellar and cytoskeletal dynamics, and some coordinated responses such as proliferation and programmed cell death. Throughout the course we will see how general cell biology can be specialized to achieve specific cellular functions through regulation of the basic machinery. We will also explore the cellular and molecular bases for a variety of human pathologies, with an emphasis on cancer. In addition to lecture, we will spend some time discussing the material, including selected articles from the primary literature, and learning through group presentations.
Introduction to cell biological techniques used to investigate structural, molecular, and physiological aspects of eukaryotic cells and their organization into tissues. Techniques include light and electron microscopy, cell culture, isolation of cellular organelles, protein electrophoresis, and Western Blot analysis.
Introduction to animal developmental biology and its applications. This course will examine the basic mechanisms through which animal bodies organize themselves, from an integrative perspective at the levels of genes and gene networks, cell properties and behaviors, coordinated interactions of cells in developing tissues, organs and organ systems, and the role of developmental processes in morphological evolution. Topics include: fertilization, cleavage and gastrulation, establishment of body axes, neural development, organ formation, tissue and organ regeneration, stem cells and medical applications, evolution of developmental programs, and teratogenesis.
Prerequisites: BIOL BC1500, BIOL BC1501, BIOL BC1502, BIOL BC1503 or the equivalent. This course examines how mammals carry out basic functions like manipulating objects, sensing the external world, oxygenating tissues, and processing food. Emphasis is placed on (a) how the body regulates itself through the integrated action of multiple organ systems and (b) what goes awry in disease.
Prerequisites: BIOL BC1502 + BIOL BC1503, and either BIOL BC1500 + BIOL BC1501 or NSBV BC1001 or permission from the instructor. Structure and function of neural membranes; ionic basis of membrane potential and action potential; synaptic transmission and neurochemistry; sensory transduction and processing; reflexes and spinal cord physiology; muscle structure and function; neuronal circuitry; and nervous system development.
Required for all majors who do not select the year-long Senior Thesis Research & Seminar (BIOL BC3593 & BC3594) to fulfill their senior capstone requirement. These seminars allow students to explore the primary literature in the Biological Sciences in greater depth than can be achieved in a lecture course. Attention will be focused on both theoretical and empirical work. Seminar periods are devoted to oral reports and discussion of assigned readings and student reports. Students will write one extensive literature review of a topic related to the central theme of the seminar section.
Topics vary per semester and include, but are not limited to:
Plant Development
,
Animal Development & Evolution,
Molecular Evolution, Microbiology & Global Change, Genomics, Comparative & Reproductive Endocrinology, and Data Intensive Approaches in Biology.
This year-long course is open to junior and senior Biology majors and minors. Students will complete an independent research project in Biology under the guidance of a faculty mentor at Barnard or another local institution. Attendance at the weekly seminar is required. By the end of the year, students will write a scientific paper about their project and give a poster presentation about their research at the Barnard Biology Research Symposium.
Completion of this year-long course fulfills two upper-level laboratory requirements for the Biology major or minor. This course must be taken in sequence, beginning with BIOL BC3591 in the Fall and continuing with BIOL BC3592 in the Spring. Acceptance into this course requires confirmation of the research project by the course instructors. A Barnard internal mentor is required if the research project is not supervised by a Barnard faculty member. This course cannot be taken at the same time as BIOL BC3593-BIOL BC3594.
This year-long course is open to junior and senior Biology majors and minors. Students will complete an independent research project in Biology under the guidance of a faculty mentor at Barnard or another local institution. Attendance at the weekly seminar is required. By the end of the year, students will write a scientific paper about their project and give a poster presentation about their research at the Barnard Biology Research Symposium.
Completion of this year-long course fulfills two upper-level laboratory requirements for the Biology major or minor. This course must be taken in sequence, beginning with BIOL BC3591 in the Fall and continuing with BIOL BC3592 in the Spring. Acceptance into this course requires confirmation of the research project by the course instructors. A Barnard internal mentor is required if the research project is not supervised by a Barnard faculty member. This course cannot be taken at the same time as BIOL BC3593-BIOL BC3594.
This year-long course is open to senior Biology majors. Students will complete an independent research project in Biology under the guidance of a faculty mentor at Barnard or another local institution. Attendance at the weekly seminar is required. By the end of the year, students will write a scientific paper about their project and give an oral presentation about their research at the Barnard Biology Research Symposium.
Completion of this year-long course fulfills the senior capstone requirement for the Biology major. This course must be taken in sequence, beginning with BIOL BC3593 in the Fall and continuing with BIOL BC3594 in the Spring. Acceptance into this course requires confirmation of the research project by the course instructors. A Barnard internal mentor is required if the research project is not supervised by a Barnard faculty member. This course cannot be taken at the same time as BIOL BC3591-BIOL BC3592.
Similar to BIOL BC3591-BIOL BC3592, this is a one-semester course that provides students with degree credit for unpaid research
without
a seminar component. You may enroll in BIOL BC3597 for between 1-4 credits per semester. As a rule of thumb, you should be spending approximately 3 hours per week per credit on your research project.
A
Project Approval Form
must be submitted to the department each semester that you enroll in this course. Your Barnard research mentor (if your lab is at Barnard) or internal adviser in the Biology Department (if your lab is elsewhere) must approve your planned research
before
you enroll in BIOL BC3597. You should sign up for your mentor's section.
This course does not fulfill any Biology major requirements. It is open to students beginning in their first year.