Foundations of Biology
General Chemistry I is a pre-requisite; General Chemistry II is a pre/co-requisite. In this course, we will introduce basic terminology, important concepts, and basic problem-solving skills in order to prepare biology and pre-health students for the challenging Biology courses they will take at Columbia. We will do a deep dive into a small number of topics and use these as access points to teaching skills that will aid students in future STEM courses. Classes will include time for problem solving. Recitations will involve problem solving and student presentations of solutions to problems.
- MW 4:10 p.m.-5:25 p.m.
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Instructor:
Mary Ann Price
CULPA: 5 Info - 2 points
INTRO BIO II:CELL BIO,DEV/PHYS
Prerequisites: BIOL UN2005, or the instructors permission. Lecture and recitation. Recommended second term of biology for majors in biology and related majors, and for premedical students. Cellular biology and development; physiology of cells and organisms. SPS, Barnard, and TC students may register for this course, but they must first obtain the written permission of the instructor, by filling out a paper Registration Adjustment Form (Add/Drop form). The form can be downloaded at the URL below, but must be signed by the instructor and returned to the office of the registrar.
http://registrar.columbia.edu/sites/default/files/content/reg-adjustment.pdf
. Students must register for a recitation section BIOL UN2016. Course website:
https://biology.columbia.edu/content/intro-bio
- TR 10:10 a.m.-11:25 a.m.
- TR 4:10 p.m.-5:25 p.m.
- 4 points
INTRO BIO II:CELL BIO,DEV/PHYS
Prerequisites: Prerequisites: Course does not fulfill Biology major requirements or premedical requirements. Enrollment in laboratory limited to 16 students per section. Corequisites: BIOL UN2006 Prerequisites: Course does not fulfill Biology major requirements or premedical requirements. Enrollment in laboratory limited to 16 students per section. Exploration of the major discoveries and ideas that have revolutionized the way we view organisms and understand life. The basic concepts of cell biology, anatomy and physiology, genetics, evolution, and ecology will be traced from seminal discoveries to the modern era. The laboratory will develop these concepts and analyze biological diversity through a combined experimental and observational approach.
- M 6:10 p.m.-8 p.m.
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Instructor:
Mary Ann Price
CULPA: 5 Info - 0 points
INTRO BIO II:CELL BIO,DEV/PHYS
Prerequisites: Prerequisites: Course does not fulfill Biology major requirements or premedical requirements. Enrollment in laboratory limited to 16 students per section. Corequisites: BIOL UN2006 Prerequisites: Course does not fulfill Biology major requirements or premedical requirements. Enrollment in laboratory limited to 16 students per section. Exploration of the major discoveries and ideas that have revolutionized the way we view organisms and understand life. The basic concepts of cell biology, anatomy and physiology, genetics, evolution, and ecology will be traced from seminal discoveries to the modern era. The laboratory will develop these concepts and analyze biological diversity through a combined experimental and observational approach.
- M 6:10 p.m.-8 p.m.
- T 8:10 a.m.-10 a.m.
- T 12:10 p.m.-2 p.m.
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Instructor:
Mary Ann Price
CULPA: 5 Info - 0 points
INTRO BIO II:CELL BIO,DEV/PHYS
Prerequisites: Prerequisites: Course does not fulfill Biology major requirements or premedical requirements. Enrollment in laboratory limited to 16 students per section. Corequisites: BIOL UN2006 Prerequisites: Course does not fulfill Biology major requirements or premedical requirements. Enrollment in laboratory limited to 16 students per section. Exploration of the major discoveries and ideas that have revolutionized the way we view organisms and understand life. The basic concepts of cell biology, anatomy and physiology, genetics, evolution, and ecology will be traced from seminal discoveries to the modern era. The laboratory will develop these concepts and analyze biological diversity through a combined experimental and observational approach.
- T 12:10 p.m.-2 p.m.
- T 6:10 p.m.-8 p.m.
- W 12:10 p.m.-2 p.m.
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Instructor:
Mary Ann Price
CULPA: 5 Info - 0 points
INTRO BIO II:CELL BIO,DEV/PHYS
Prerequisites: Prerequisites: Course does not fulfill Biology major requirements or premedical requirements. Enrollment in laboratory limited to 16 students per section. Corequisites: BIOL UN2006 Prerequisites: Course does not fulfill Biology major requirements or premedical requirements. Enrollment in laboratory limited to 16 students per section. Exploration of the major discoveries and ideas that have revolutionized the way we view organisms and understand life. The basic concepts of cell biology, anatomy and physiology, genetics, evolution, and ecology will be traced from seminal discoveries to the modern era. The laboratory will develop these concepts and analyze biological diversity through a combined experimental and observational approach.
- W 12:10 p.m.-2 p.m.
- W 2:10 p.m.-4 p.m.
- W 4:10 p.m.-6 p.m.
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Instructor:
Mary Ann Price
CULPA: 5 Info - 0 points
INTRO BIO II:CELL BIO,DEV/PHYS
Prerequisites: Prerequisites: Course does not fulfill Biology major requirements or premedical requirements. Enrollment in laboratory limited to 16 students per section. Corequisites: BIOL UN2006 Prerequisites: Course does not fulfill Biology major requirements or premedical requirements. Enrollment in laboratory limited to 16 students per section. Exploration of the major discoveries and ideas that have revolutionized the way we view organisms and understand life. The basic concepts of cell biology, anatomy and physiology, genetics, evolution, and ecology will be traced from seminal discoveries to the modern era. The laboratory will develop these concepts and analyze biological diversity through a combined experimental and observational approach.
- W 4:10 p.m.-6 p.m.
- W 8:10 p.m.-10 p.m.
- R 12:10 p.m.-2 p.m.
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Instructor:
Mary Ann Price
CULPA: 5 Info - 0 points
CONTMP BIO II:CELL BIO,DEV,PHYS
Prerequisites: a course in college chemistry and BIOL UN2005 or BIOL UN2401, or the written permission of either the instructor or the premedical adviser. Cellular biology and development; physiology of cells and organisms. Same lectures as BIOL UN2006, but recitation is optional. For a detailed description of the differences between the two courses, see the course web site or http://www.columbia.edu/cu/biology/ug/advice/faqs/gs.html. Website: http://www.columbia.edu/cu/biology/courses/c2006/ , SPS, Barnard, and TC students may register for this course, but they must first obtain the written permission of the instructor, by filling out a paper Registration Adjustment Form (Add/Drop form). The form can be downloaded at the URL below, but must be signed by the instructor and returned to the office of the registrar. http://registrar.columbia.edu/sites/default/files/content/reg-adjustment.pdf
- TR 10:10 a.m.-11:25 a.m.
- TR 4:10 p.m.-5:25 p.m.
- 3 points
CONTEMPORARY BIOLOGY LAB
Prerequisite or corequisite: BIOL UN2005 or BIOL UN2401. Contemporary Biology Lab is designed to provide students with hands-on exploration of fundamental and contemporary biological tools and concepts. Activities include in depth study of mammalian anatomy and physiology through dissection and histology, as well as a series of experiments in genetics and molecular biology, with emphasis on data analysis and experimental technique.
- M 1:10 p.m.-5 p.m.
- T 1:10 p.m.-5 p.m.
- W 1:10 p.m.-5 p.m.
- R 5:40 p.m.-9:30 p.m.
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Instructor:
Ava E Brent
Info -
Instructor:
Joshua P Abrams
Info -
Instructor:
Ava E Brent
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Instructor:
Joshua P Abrams
Info - 3 points
NEUROBIO II: DEVPT & SYSTEMS
Prerequisites: BIOL UN3004, one year of biology, or the instructors permission. This course is the capstone course for the Neurobiology and Behavior undergraduate major at Columbia University and will be taught by the faculty of the Kavli Institute of Brain Science: http://www.kavli.columbia.edu/ Science: http://www.kavli.columbia.edu/. It is designed for advanced undergraduate and graduate students. Knowledge of Cellular Neuroscience (how an action potential is generated and how a synapse works) will be assumed. It is strongly recommended that students take BIOL UN3004 Neurobiology I: Molecular and Cellular Neuroscience, or a similar course, before enrolling in BIOL UN3005. Students unsure about their backgrounds should check a representative syllabus of BIOL UN3004 on the BIOL UN3004 website (http://www.columbia.edu/cu/biology/courses/w3004/). Website for BIOL UN3005: http://www.columbia.edu/cu/biology/courses/w3005/index.html
- TR 10:10 a.m.-11:25 a.m.
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Instructor:
Darcy B Kelley
CULPA: 4
Wikipedia
Info
- 4 points
PHYSIOLOGY
In this primarily human physiology course, we will discuss how the major organ systems function, with an emphasis on cellular, molecular, and physical mechanisms. Organ systems covered include musculoskeletal, cardiovascular, respiratory, urinary, and digestive systems. Traditional lectures focus primarily on the normal functioning of organ systems, while pathophysiology is introduced through five case studies during the semester. After this course, students should be able to 1) describe the basic functioning of the major organ systems and how they contribute to homeostasis and health, 2) apply key concepts in physics and chemistry, such as flow, pressure/volume relationships, and mass action, to physiological systems, 3) use key concepts in molecular and cell biology to gain a mechanistic understanding of physiological processes, explain how organ systems work in an integrated way to achieve homeostasis and health, and 4) predict changes in organ function upon drug treatment, genetic mutation, or disease conditions.
- TR 1:10 p.m.-2:25 p.m.
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Instructor:
Ava E Brent
Info - 3 points
Neurobiology II Recitation
Discussion/recitation section for BIOL UN3005 Neurobiology II
- M 6 p.m.-7:10 p.m.
- T 9 a.m.-10:10 a.m.
- W 5 p.m.-6:10 p.m.
- W 6 p.m.-7:10 p.m.
- R 5 p.m.-6:10 p.m.
- F 1 p.m.-2:10 p.m.
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Instructor:
Abhishek Shah
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Instructor:
Brittany M Bistis
Info -
Instructor:
Shaoyi Sheng
Info -
Instructor:
Simon O Ogundare
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Instructor:
Bovey Y Rao
Info -
Instructor:
Emily K Eichenholtz
Info - 0 points
Brain Evolution
If an engineer were to build “the brain”, they would not be able to reproduce any of the brains that exist on Earth. Our brains were not designed to be perfect, but are a result of millions of years of evolution and adaptation. The goal of this course is to provide an overview of brain evolution, ranging from the evolution of the first neurons to the origin of the human brain. Specifically, the course will focus on recent insights emerging from studies of development, gene expression, and neural circuit architecture. The evolutionary perspective on commonly used terms, such as “neuron” and “brain”, and general principles of brain organization and function emerging from comparative studies will be discussed.
- R 2:10 p.m.-4 p.m.
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Instructor:
Maria Tosches
Info - 3 points
GENETICS
Prerequisites: BIOL UN2005 and BIOL UN2006. General genetics course focused on basic principles of transmission genetics and the application of genetic approaches to the study of biological function. Principles will be illustrated using classical and contemporary examples from prokaryote and eukaryote organisms, and the experimental discoveries at their foundation will be featured. Applications will include genetic approaches to studying animal development and human diseases. SPS and TC students must obtain the written permission from the instructor, by filling out a Registration Adjustment Form (Add/Drop form). https://www.registrar.columbia.edu/sites/default/files/content/reg-adjustment.pdf
- TR 10:10 a.m.-11:25 a.m.
- 3 points
PROJECT LAB-MOLECULAR GENETICS
Multicellular animals contain a diverse array of cell types, yet start from a single cell. How do cells decide what kind of cell to be? In this lab course, we will use the tools of molecular biology and genetics to explore this fascinating question. We will use the nematode
Caenorhabditis elegans
, a powerful model organism used in hundreds of research labs. The course will be divided into three modules:
C. elegans
genetics, molecular cloning, and genetic screening. Laboratory techniques will include PCR, gel electrophoresis, restriction digest, ligation, transformation, RNAi, and
C. elegans
maintenance. Students will pursue original projects; emphasis will be placed on scientific thinking and scientific communication. SPS and TC students may register for this course, but they must first obtain the written permission of the instructor, by filling out a paper Registration Adjustment Form (Add/Drop form). Prerequisites: UN2005/UN2401 and UN2006/UN2402, or the equivalent at a different institution.
- TR 1:10 p.m.-5 p.m.
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Instructor:
Michelle Attner
Info - 5 points
Biochemistry
Prerequisites: 1 year of Introductory Biology, 1 year General Chemistry, and 1st semester Organic Chemistry. Biochemistry is the study of the chemical processes within organisms that give rise to the immense complexity of life. This complexity emerges from a highly regulated and coordinated flow of chemical energy from one biomolecule to another. This course serves to familiarize students with the spectrum of biomolecules (carbohydrates, lipids, amino acids, nucleic acids, etc.) as well as the fundamental chemical processes (glycolysis, citric acid cycle, fatty acid metabolism, etc.) that allow life to happen. The course will end with a discussion of diseases that have biochemical etiologies. In particular, this course will employ active learning techniques and critical thinking problem-solving to engage students in answering the question: how is the complexity of life possible? NOTE: While only the 1st semester of Organic Chemistry is listed as a pre-requisite, it is highly recommended that you take all of Organic Chemistry beforehand.
- T 7 p.m.-9:30 p.m.
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Instructor:
Danny N Ho
CULPA: 7 Info - 3 points
INDEP BIOLOGICAL RESEARCH - REC
- F 10 a.m.-11 a.m.
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Instructor:
Jellert T Gaublomme
Info - 0 points
MOLECULAR BIOLOGY OF CANCER
Prerequisites: three terms of biology (genetics and cell biology recommended). Cancer is one of the most dreaded common diseases. Yet it is also one of the great intellectual challenges in biology today. How does a cell become cancerous? What are the agents that cause this to occur? How do current findings about genes, cells, and organisms ranging from yeast cells to humans inform us about cancer? How do findings about cancer teach us new biological concepts? Over the past few years there have been great inroads into answering these questions which have led to new ways to diagnose and treat cancer. This course will discuss cancer from the point of view of basic biological research. We will cover topics in genetics, molecular and cell biology that are relevant to understanding the differences between normal and cancer cells. These will include tumor viruses, oncogenes, tumor suppressor genes, cell cycle regulation, programmed cell death and cell senescence. We will also study some current physiological concepts related to cancer including angiogenesis, tumor immunology, cancer stem cells, metastasis and new approaches to treatment that are built on recent discoveries in cancer biology. SPS and TC students may register for this course, but they must first obtain the written permission of the instructor, by filling out a paper Registration Adjustment Form (Add/Drop form). The form can be downloaded at the URL below, but must be signed by the instructor and returned to the office of the registrar. http://registrar.columbia.edu/sites/default/files/content/reg-adjustment.pdf
- TR 2:40 p.m.-3:55 p.m.
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Instructor:
Carol L Prives
CULPA: 2 Wikipedia Info - 3 points
TOPICS IN BIOLOGY
CROSSROADS IN BIOETHICS
Prerequisites: Introductory Biology or equivalent. Topics in Biology: Radiographic Anatomy and Select Pathology (Section 007 Fall semester) , Radiographic Anatomy and Selective Pathology is a survey course intended for undergraduate students. This course is not limited to science majors and would be of value to any student that may have an interest in studying the anatomy of the human body. The course is a systematic approach to the study of the human body utilizing medical imaging. We will be studying neuro-anatomy, anatomy of the thorax, abdomen, and pelvis. Vascular and musculoskeletal imaging will be addressed as well. Modalities will include CT, MRI, PET/CT, and Ultrasound. Cross sectional imaging will be supplemented with pathology demonstrated on appropriate cross sectional imaging. The class size will be limited to 15 students. The lecture will be offered Wednesday evenings from 6:10-7:00 pm. This will be a 1 credit course offered only during the fall semesters. Topics in Biology: Crossroads in Bioethics (Section 001 Spring semester) , This two credit multidisciplinary and interactive course will focus on contemporary issues in bioethics and medical ethics. Each topic will cover both the underlying science of new biotechnologies and the subsequent bioethical issues that emerge from these technologies. Each topic will introduce a bioethical principle that will be explored using case studies. Students are expected to prepare for each class based on the assignment so that classroom time will be devoted to discussion, case presentations, and role playing rather than merely lectures. Topics include stem cell research, human reproductive cloning, bioterrorism, neuroethics, genetic screening, medical stem cell tourism, patents and science, forensic science and the interface of science and culture/religion.
- T 1:10 p.m.-2:25 p.m.
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Instructor:
John Loike
CULPA: 8
Wikipedia
Info
- 2 points
BIOLOGY AT PHYSICAL EXTREMES
Prerequisites: one year each of biology and physics, or the instructor's permission. This is a combined lecture/seminar course designed for graduate students and advanced undergraduates. The course will cover a series of cases where biological systems take advantage of physical phenomena in counter intuitive and surprising ways to accomplish their functions. In each of these cases, we will discuss different physical mechanisms at work. We will limit our discussions to simple, qualitative arguments. We will also discuss experimental methods enabling the study of these biological systems. Overall, the course will expose students to a wide range of physical concepts involved in biological processes.
- R 2:10 p.m.-4 p.m.
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Instructor:
Ozgur Sahin
h-index: 24 Info - 3 points
ANCIENT AND MODERN RNA WORLDS
Ancient and Modern RNA Wo
RNA has recently taken center stage with the discovery that RNA molecules sculpt the landscape and information contained within our genomes. Furthermore, some ancient RNA molecules combine the roles of both genotype and phenotype into a single molecule. These multi-tasking RNAs offering a possible solution to the paradox of which came first: DNA or proteins. This seminar explores the link between modern RNA, metabolism, and insights into a prebiotic RNA world that existed some 3.8 billion years ago. Topics include the origin of life, replication, and the origin of the genetic code; conventional, new, and bizarre forms of RNA processing; structure, function and evolution of key RNA molecules, including the ribosome, and RNA therapeutics including vaccines. The format will be weekly seminar discussions with presentations. Readings will be taken from the primary literature, emphasizing seminal and recent literature. Requirements will be student presentations, class participation, and a final paper.
- W 10:10 a.m.-noon
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Instructor:
Laura Landweber
Wikipedia Info - 3 points
ETHICS IN BIOPHARM PAT/REG LAW
This course – the first of its kind at Columbia – introduces students to a vital subfield of ethics focusing on patent and regulatory law in the biotech and pharmaceutical sectors. The course combines lectures, structured debate, and research to best present this fascinating and nuanced subject. Properly exploring this branch of bioethics requires an in-depth understanding of biotech and pharmaceutical patent and regulatory law. Students can gain this understanding by first completing Biotechnology Law (BIOT GU4160), formerly the prerequisite for this course. Now, they can also gain it by reading the appropriate chapters of
Biotechnology Law: A Primer for Scientists
(the textbook for BIOT GU4160 published earlier this year) prior to each class. A number of students in the biotechnology fields (such as those in biotechnology, biomedical engineering, and bioethics programs) have shown a keen interest over the years in taking this course, yet were unable to do so because they hadn’t taken BIOT GU4160. Given the recent publication of
Biotechnology Law
and the desirability of making BIOT GU4161 accessible to more students having the appropriate science background, BIOT GU4160 has been removed as a prerequisite.
- T 6:10 p.m.-8 p.m.
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Instructor:
Alan J Morrison
Info - 3 points
SEM-BIOTECH DEVPT & REGULATION
Prerequisites: BIOT W4200 (OK without prerequisite). This course will provide a practical definition of the current role of the Regulatory Professional in pharmaceutical development, approval and post-approval actions. This will be illustrated by exploration, and interactive discussion of regulatory history, its evolution, current standards, and associated processes. The course will seek to clarify the role of Regulatory in development and lifecycle opportunities, demonstrating the value Regulatory adds by participation on research, development and commercial teams. The course will utilize weekly case studies and guest lecturers to provide color to current topical events related to the areas.
SEMINAR IN BIOTECHNOLOGY
Prerequisites: BIOL W4300 or the instructors permission. A weekly seminar and discussion course focusing on the most recent development in biotechnology. Professionals of the pharmaceutical, biotechnology, and related industries will be invited to present and lead discussions.
- W 2:10 p.m.-4 p.m.
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Instructor:
Lili Yamasaki
CULPA: 5 Info - 3 points
VIROLOGY
The basic thesis of the course is that all viruses adopt a common strategy. The strategy is simple:
1. Viral genomes are contained in metastable particles.
2. Genomes encode gene products that promote an infectious cycle (mechanisms for genomes to enter cells, replicate, and exit in particles).
3. Infection patterns range from benign to lethal; infections can overcome or co-exist with host defenses.
Despite the apparent simplicity, the tactics evolved by particular virus families to survive and prosper are remarkable. This rich set of solutions to common problems in host/parasite interactions provides significant insight and powerful research tools. Virology has enabled a more detailed understanding of the structure and function of molecules, cells and organisms and has provided fundamental understanding of disease and virus evolution.
The course will emphasize the common reactions that must be completed by all viruses for successful reproduction within a host cell and survival and spread within a host population. The molecular basis of alternative reproductive cycles, the interactions of viruses with host organisms, and how these lead to disease are presented with examples drawn from a set of representative animal and human viruses, although selected bacterial viruses will be discussed.
- MW 4:10 p.m.-5:25 p.m.
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Instructor:
Vincent R Racaniello
CULPA: 11
Wikipedia
Info
- 3 points
GENOMICS OF GENE REGULATION
- M 2:40 p.m.-5:25 p.m.
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Instructor:
Harmen Bussemaker
Wikipedia h-index: 43 Info - 4 points
Molecular Biology
Prerequisites: one year of biology. This is a lecture course designed for advanced undergraduates and graduate students. The focus is on understanding at the molecular/biochemical level how genetic information is stored within the cell, how it is replicated and expressed, and how it is regulated. Topics covered include genome organization, DNA replication and repair, transcription, RNA processing, and translation. This course will also emphasize the critical analysis of the scientific literature and help students understand how to identify important biological problems and how to address them experimentally. SPS and TC students may register for this course, but they must first obtain the written permission of the instructor, by filling out a paper Registration Adjustment Form (Add/Drop form). The form can be downloaded at the URL below, but must be signed by the instructor and returned to the office of the registrar.
http://registrar.columbia.edu/sites/default/files/content/reg-adjustment.pdf
- W 2:40 p.m.-3:55 p.m.
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Instructor:
Alice Heicklen
CULPA: 15 Info - 3 points
A Structural View of Biology
The course covers a general introduction to the theory and experimental techniques of structural biology (protein expression and purification, protein crystallography, cryo-electron microscopy, nuclear magnetic resonance) and then how to use the structural information to understand biochemical and biological processes. The first part of the course will cover the general introduction to structural biology. The second part of the course will involve discussions and explorations of various structures, led by the instructor but with substantial participation from the students, to understand the molecular mechanisms of selected biochemical and biological processes. In the final part of the course, each student will select and lead discussions on a primary structural biology paper. The overall goal of the course is to increase the understanding of how protein structures are determined, what protein structures look like, and how to use the structures to understand biology.
- TR 10:10 a.m.-11:25 a.m.
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Instructor:
Liang Tong
CULPA: 8 Wikipedia h-index: 85 Info - 3 points
NEUROBIO II: DEVPT & SYSTEMS
Prerequisites: BIOL W4004, one year of biology, or the instructors permission. This course is a graduate seminar in Developmental and Systems Neuroscience for students matriculated in a PhD program in Neuroscience. Undergraduate students should instead enroll in UN3005.
- TR 10:10 a.m.-11:25 a.m.
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Instructor:
Darcy B Kelley
CULPA: 4
Wikipedia
Info
- 3 points
Genetics
Prerequisites: BIOL UN2005 and BIOL UN2006 or the equivalent. General genetics course focused on basic principles of transmission genetics and the application of genetic approaches to the study of biological function. Principles will be illustrated using classical and contemporary examples from prokaryote and eukaryote organisms, and the experimental discoveries at their foundation will be featured. Applications will include genetic approaches to studying animal development and human diseases. All students must get permission from the instructor to be added from the waitlist.
- TR 10:10 a.m.-11:25 a.m.
- 3 points
Intro to Management Principles - Applica
Intro Biopharma Mgmt Prin
Students in the MA in Biotechnology Program at Columbia commonly go on to pursue careers in the biopharmaceutical industry. The departmental training focus is technical. However, a basic understanding of management principles can be highly beneficial for optimizing job performance as well as for job advancement, and is commonly a challenging new skill to be mastered by new technical hires in the biopharmaceutical industry.
This course has two components: 1) a survey of the basic elements of management education and 2) a series of actual cases taken from the biopharmaceutical industry which will allow students to see how the basic management principles they have learned are applied.
The cases cover a range of business areas with an emphasis on the effects of business decisions on R&D operations and productivity. Cases will involve strategies for R&D management, strategies for business operation/expansion, issues of licensing /acquisition versus in house discovery of new products, generics versus brand name proprietary drug businesses, managing mergers and acquisitions and entrepreneurship.
Cases will be rigorously discussed and debated in class. There is no single route to good management practice or corporate success, so in many instances diametrically opposed opinions will both have merit. As some students will have had workplace exposure, students should bring such experience and knowledge to case discussions. The course will thus be in good part taught using the Socratic Method.
- F 12:10 p.m.-2 p.m.
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Instructor:
Donald Kirsch
Info - 3 points
MOLECULAR BIOLOGY OF CANCER
- TR 2:40 p.m.-3:55 p.m.
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Instructor:
Carol L Prives
CULPA: 2 Wikipedia Info - 3 points
WRITING FOR THE BIOLOGICAL SCI
This is a required science writing course for the PhD in Biological Sciences, open only to second year PhD. candidates in Biological Sciences. In this course, we will read examples of science writing from the recent literature, consider the strategies used by successful writers, and workshop student writing. The course will emphasize techniques for achieving clarity of thought and clear prose style while communicating science to other scientists. Students will write three short papers and two longer papers culminating in a Proposed Research Plan.
- W 4:10 p.m.-5:25 p.m.
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Instructor:
Meehan J Crist
Info - 2 points
Readings in Evolutionary Genomics
Readings Evolutionary Gen
The course covers a range of current topics in evolutionary and quantitative genetics, with two main aims: 1) to expose students to important, open questions in the field and 2) to help them learn how to read research papers carefully and critically. This year we will focus on the genetic basis of adaptation. Adaptation is the dynamic evolutionary process by which an organism’s fitness increases in a particular environment via changes in the frequencies of alleles contributing to heritable phenotypic trait variation. Recent evidence from human genetics, and past evidence in quantitative genetics in a variety of organisms, indicate the heritable variation in many traits is highly polygenic, suggesting that when selection pressures change, adaptation should be highly polygenic as well. At the same time, there appear to be many examples in which adaptation occured by large effect changes in few genes. We will review the theory and evidence, with the goal of understanding when we should expect adaptation to proceed by these different modes.
- T 2:10 p.m.-4 p.m.
- 3 points